 Dental bone substitute materials in dental implantologyDental bone substitute materials in severe periodontal diseaseRegeneration in mild periodontal diseaseCoated dental implants for critical implantation sitesOrthopaedic bone substitute materials in spinal fusionOrthopaedic bone substitute materials in fractures/traumaCartilage regenerative materials in osteochondral defectsRegenerative treatment of osteoarthritis |
Medical ApplicationsRegenerative medicine as a therapeutic approach is changing the practice of orthopaedics and dentistry. Rather than replacing bone and cartilage with synthetic alternatives or metal components, regenerative medicine seeks to encourage tissues renewal and repair through the stimulation of natural healing processes. Scil Technology’s product initiatives are targeted at various dental and orthopaedic indications with a high medical need such as dental implantology and periodontal disease or major orthopaedic indications like spinal fusion, fractures, cartilage defects, osteoarthritis, and degenerative disc disease. </span> Today, stimulation of tissue regeneration which is essential for appropriate tissue healing remains a challenge. In bone and cartilage repair, the use of the patient’s own tissue (autologous tissue or an autograft) to stimulate tissue healing is defined as the gold standard in these areas. </span>However, it is well known that the use of autograft is often correlated with various drawbacks for clinical use, including cost, the risk and inconvenience for the patient associated with a second surgical intervention and limited efficacy in critical cases. Scil is therefore focusing on the development of (a) specific growth factor(s) combined with biodegradable substituting material that is able to induce tissue healing as an effective alternative to autologous grafting.
Dental productsScil Technology’s dental product candidates are targeted at <link 72 - internal-link "Öffnet internen Link im aktuellen Fenster">dental implantology and > class="internal-link" >eriodontal disease. Whereas the objective of dental implantology is the aesthetic replacement of missing teeth treatment of periodontal disease aims at the preservation of teeth. Both fields require products for tissue restoration, namely bone, soft tissue and/or periodontal ligament. Orthopaedic productsScil Technology is developing products targeted at two of the largest segments for bone formation in orthopaedics: spinal fusions and > class="internal-link" >ractures/trauma. Both therapeutic areas lend themselves well to Scil Technology’s approach of developing innovative biomaterials with improved patients´ benefit. <span lang="EN-GB">In the area of cartilage repair, Scil Technology has several innovative programmes targeting the treatment from focal chondral or > class="internal-link" >steochondral defects resulting from traumatic joint injury, to severe > class="internal-link" >steoarthritis. Currently, no tissue regenerative products are available to effectively induce the renewal of cartilage from patients suffering from osteochondral defects or osteoarthritis.
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